Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 13/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 7/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20348950 | 0.85 | PTPN1 (0.54) | MEN1KMT2AATMPOLBPSMD14 | |
| SCHEMBL20339693 | 0.83 | PTPN1 (0.67) | MEN1KMT2AATMPOLBALDH1A1 | |
| SCHEMBL20339691 | 0.83 | PTPN1 (0.67) | MEN1KMT2AATMPOLBALDH1A1 | |
| SCHEMBL20339741 | 0.77 | NLRP3 (0.61) | PTPN1NLRP3 | |
| SCHEMBL20339740 | 0.77 | NLRP3 (0.61) | PTPN1NLRP3 | |
| SCHEMBL20339702 | 0.70 | PTPN1 (0.66) | MEN1KMT2APOLBALDH1A1MAPK1 | |
| SCHEMBL20339701 | 0.70 | PTPN1 (0.66) | MEN1KMT2APOLBALDH1A1MAPK1 | |
| SCHEMBL2080494 | 0.68 | MEN1 (0.82) | MEN1KMT2AATMPOLBPSMD14 | |
| SCHEMBL2080496 | 0.68 | MEN1 (0.82) | MEN1KMT2AATMPOLBPSMD14 | |
| SCHEMBL19999130 | 0.68 | MEN1 (0.74) | MEN1KMT2AATMPOLBPSMD14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018126072-A1 | HETEROCYCLIC INTEGRIN AGONISTS | ADHAERE PHARMACEUTICALS, INC. (US) | 2018-07-05 | — | — | WO | disclosed |