Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 5/20 | 0.60 |
| ▸ | BLK | P51451 | 4/20 | 0.60 |
| ▸ | BMX | P51813 | 4/20 | 0.60 |
| ▸ | JAK3 | P52333 | 4/20 | 0.60 |
| ▸ | BTK | Q06187 | 4/20 | 0.60 |
| ▸ | NR2C2 | P49116 | 1/20 | 0.60 |
| ▸ | CLK1 | P49759 | 1/20 | 0.60 |
| ▸ | CLK2 | P49760 | 1/20 | 0.60 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.60 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.60 |
| ▸ | TEC | P42680 | 1/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.48 |
| ▸ | PIK3C2A | O00443 | 1/20 | 0.48 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.48 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.48 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.48 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.48 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20348942 | 0.88 | PIK3CA (0.68) | MTORBLKBMXJAK3BTK | |
| SCHEMBL20348944 | 0.86 | PIK3CA (0.66) | MTORBLKBMXJAK3BTK | |
| SCHEMBL6876259 | 0.81 | MTOR (0.58) | MTORBLKBMXJAK3BTK | |
| SCHEMBL6873707 | 0.80 | PIK3CA (0.73) | MTORBLKBMXJAK3BTK | |
| SCHEMBL20355911 | 0.80 | PIK3CA (0.68) | MTORPIK3CAPIK3CDPIK3C2APIK3C2B | |
| SCHEMBL20348943 | 0.78 | MTOR (0.66) | MTORPIK3CAPIK3CDPIK3C2APIK3C2B | |
| SCHEMBL7918796 | 0.78 | MTOR (0.79) | MTORBLKBMXJAK3BTK | |
| SCHEMBL7920885 | 0.77 | MTOR (0.58) | MTORPIK3CADYRK1APIK3CDPIK3C2A | |
| SCHEMBL7912460 | 0.76 | MTOR (0.67) | MTORBLKBMXJAK3BTK | |
| SCHEMBL7926734 | 0.76 | BMX (0.64) | MTORBLKBMXJAK3BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180185374-A1 | INHIBITORS OF MTOR KINASE AS ANTI-VIRAL AGENTS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2018-07-05 | — | — | US | disclosed |
| US-20180185374-A1 | INHIBITORS OF MTOR KINASE AS ANTI-VIRAL AGENTS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2018-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180185374-A1 | INHIBITORS OF MTOR KINASE AS ANTI-VIRAL AGENTS | EIF2AK2, MTOR, EIF4EBP1 | MTOR 2/4885BLK 1195/4885BMX 1318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.