Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 13/20 | 0.70 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20349923 | 0.91 | MAOA (0.68) | MAOANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL20346697 | 0.88 | MAOA (0.58) | MAOANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL20346583 | 0.85 | MAOA (0.67) | MAOANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL20349952 | 0.85 | MAOA (0.56) | MAOANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL20350130 | 0.84 | MAOA (0.51) | MAOANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL20329732 | 0.84 | MAOA (0.76) | MAOANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL20329620 | 0.84 | MAOA (0.76) | MAOANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7335491 | 0.83 | MAOA (1.00) | MAOANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL28846469 | 0.82 | MAOA (0.52) | MAOANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL30091399 | 0.82 | MAOA (0.52) | MAOANPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180185325-A1 | 12H-BENZO[b]XANTHEN-12-ONES, COMPOSITIONS CONTAINING, AND USES OF, SAME | THESAN PHARMACEUTICALS, INC. (US) | 2018-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180185325-A1 | 12H-BENZO[b]XANTHEN-12-ONES, COMPOSITIONS CONTAINING, AND USES OF, SAME | AHR, NR1H2, NR1H3 | MAOA 408/4885NPC1 347/4885RAB9A 3885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.