SCHEMBL20351963

SCHEMBL20351963

Nc1nc(C(O)Nc2cc(-c3ccc(OC4CCNC4)nc3)ccc2Cl)co1

nearest known ligand 0.70

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PAICS P22234 20/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20352154 0.83 PAICS (1.00) PAICS
SCHEMBL20338935 0.77 PAICS (1.00) PAICS
SCHEMBL20352004 0.70 PAICS (0.73) PAICS
SCHEMBL20338920 0.68 PAICS (1.00) PAICS
SCHEMBL20338938 0.67 PAICS (1.00) PAICS
SCHEMBL7464016 0.65 PAICS (0.48) PAICS
SCHEMBL20338890 0.65 PAICS (0.75) PAICS
SCHEMBL13560051 0.63 HTR2C (0.48)
SCHEMBL4823398 0.63 HTR2C (0.48)
SCHEMBL21571594 0.60 PAICS (1.00) PAICS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018122550-A1 OXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER LIFEARC (GB) 2018-07-05 WO disclosed