Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAICS | P22234 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6886586 | 0.79 | FAAH (0.46) | TDO2MKNK1MKNK2FAAH | |
| SCHEMBL6786345 | 0.78 | TDO2 (0.66) | PAICSTDO2MKNK1MKNK2HRH1 | |
| SCHEMBL18077122 | 0.78 | TDO2 (0.52) | CHRNB2CHRNA4TDO2PRKCZ | |
| SCHEMBL26774162 | 0.78 | CHRNB2 (0.47) | CHRNB2CHRNA4TDO2MKNK1PRKCZ | |
| SCHEMBL26774172 | 0.78 | CHRNB2 (0.47) | CHRNB2CHRNA4TDO2MKNK1PRKCZ | |
| SCHEMBL4828298 | 0.78 | CHRNB2 (0.47) | CHRNB2CHRNA4TDO2MKNK1PRKCZ | |
| SCHEMBL4823398 | 0.78 | HTR2C (0.48) | CHRNB2CHRNA4 | |
| SCHEMBL13560051 | 0.78 | HTR2C (0.48) | CHRNB2CHRNA4 | |
| SCHEMBL28671432 | 0.78 | TDO2 (0.52) | CHRNB2CHRNA4TDO2PRKCZ | |
| SCHEMBL26774177 | 0.78 | CHRNB2 (0.47) | CHRNB2CHRNA4TDO2MKNK1PRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212319-A2 | 3-PYRROLIDINYLOXY-3'-PYRIDYL ETHER COMPOUNDS USEFUL FOR CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | Abbott Laboratories (US) | 2002-06-12 | — | — | EP | claimed |
| WO-2001019817-A2 | 3-PYRROLIDINYLOXY-3'-PYRIDYL ETHER COMPOUNDS USEFUL FOR CONTROLLING CHEMICAL SYNAPTIC TRANSMISSION | ABBOTT LABORATORIES (US) | 2001-03-22 | — | — | WO | claimed |