Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAICS | P22234 | 13/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | PI4KA | P42356 | 2/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.36 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20352106 | 0.75 | PAICS (0.60) | PAICSNTRK1 | |
| SCHEMBL21571623 | 0.72 | PAICS (1.00) | PAICS | |
| SCHEMBL20338968 | 0.68 | PAICS (1.00) | PAICS | |
| SCHEMBL20351973 | 0.64 | PAICS (1.00) | PAICS | |
| SCHEMBL24247927 | 0.63 | PAICS (0.72) | PAICS | |
| SCHEMBL20352039 | 0.61 | PAICS (0.36) | PAICSNAMPT | |
| SCHEMBL20338965 | 0.61 | PAICS (0.90) | PAICS | |
| SCHEMBL20350481 | 0.59 | PAICS (1.00) | PAICS | |
| SCHEMBL21571611 | 0.58 | PAICS (1.00) | PAICS | |
| SCHEMBL19005073 | 0.58 | PIK3CD (0.52) | PAICSPIK3CAPIK3CDPIK3CBPI4KA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122550-A1 | OXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | LIFEARC (GB) | 2018-07-05 | — | — | WO | disclosed |