Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAICS | P22234 | 9/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20351965 | 0.61 | PAICS (0.56) | PAICSNAMPT | |
| SCHEMBL19005073 | 0.57 | PIK3CD (0.52) | PAICS | |
| SCHEMBL15378667 | 0.56 | NAMPT (0.50) | NAMPT | |
| SCHEMBL19004903 | 0.55 | PIK3CD (0.39) | PAICSNAMPT | |
| SCHEMBL19005096 | 0.55 | PAICS (0.38) | PAICSNAMPT | |
| SCHEMBL19005196 | 0.55 | PIK3CD (0.55) | PAICS | |
| SCHEMBL20732675 | 0.55 | JAK2 (0.39) | PAICSNAMPT | |
| SCHEMBL7928721 | 0.55 | BACE1 (0.47) | PAICSNAMPT | |
| SCHEMBL19005094 | 0.55 | PAICS (0.37) | PAICSNAMPT | |
| SCHEMBL19005296 | 0.54 | PIK3CD (0.50) | PAICS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122550-A1 | OXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | LIFEARC (GB) | 2018-07-05 | — | — | WO | disclosed |