Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAICS | P22234 | 14/20 | 0.49 |
| ▸ | MET | P08581 | 5/20 | 0.41 |
| ▸ | WNT1 | P04628 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20351938 | 0.83 | PAICS (0.64) | PAICSMETGSK3BDYRK1A | |
| SCHEMBL21571620 | 0.81 | PAICS (0.73) | PAICS | |
| SCHEMBL20351947 | 0.80 | PAICS (0.52) | PAICSMET | |
| SCHEMBL20340347 | 0.77 | PAICS (0.70) | PAICS | |
| SCHEMBL24247856 | 0.75 | PAICS (0.69) | PAICS | |
| SCHEMBL20338912 | 0.74 | PAICS (0.72) | PAICS | |
| SCHEMBL21579051 | 0.72 | PAICS (0.50) | PAICSWNT1GSK3BDYRK1A | |
| SCHEMBL24247969 | 0.72 | PAICS (0.48) | PAICSMETWNT1GSK3BDYRK1A | |
| SCHEMBL20352022 | 0.71 | PAICS (0.46) | PAICSMET | |
| SCHEMBL21571622 | 0.68 | PAICS (0.70) | PAICS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122550-A1 | OXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | LIFEARC (GB) | 2018-07-05 | — | — | WO | disclosed |