Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAICS | P22234 | 7/20 | 0.46 |
| ▸ | MET | P08581 | 8/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20338912 | 0.79 | PAICS (0.72) | PAICS | |
| SCHEMBL21571620 | 0.71 | PAICS (0.73) | PAICS | |
| SCHEMBL20352046 | 0.71 | PAICS (0.49) | PAICSMET | |
| SCHEMBL20340347 | 0.70 | PAICS (0.70) | PAICS | |
| SCHEMBL20351947 | 0.70 | PAICS (0.52) | PAICSMET | |
| SCHEMBL24247856 | 0.68 | PAICS (0.69) | PAICS | |
| SCHEMBL21571622 | 0.67 | PAICS (0.70) | PAICS | |
| SCHEMBL24247969 | 0.66 | PAICS (0.48) | PAICSMETRET | |
| SCHEMBL12179247 | 0.65 | PIK3CA (0.46) | METPIK3CDKDRPIK3CAPIK3CB | |
| SCHEMBL1581859 | 0.65 | MET (0.71) | METKDRPIK3CAEGFRRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122550-A1 | OXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | LIFEARC (GB) | 2018-07-05 | — | — | WO | disclosed |