Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAICS | P22234 | 11/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20352035 | 0.89 | PAICS (0.67) | PAICSHDAC3KCNH2HDAC2HDAC1 | |
| SCHEMBL20339057 | 0.88 | PAICS (0.53) | PAICSHDAC3KCNH2HDAC2HDAC1 | |
| SCHEMBL20352082 | 0.86 | PAICS (0.51) | PAICSHDAC3KCNH2HDAC2HDAC1 | |
| SCHEMBL21571618 | 0.82 | PAICS (0.76) | PAICSKCNH2 | |
| SCHEMBL20352042 | 0.80 | PAICS (0.40) | PAICSHDAC3KCNH2HDAC2 | |
| SCHEMBL24220495 | 0.79 | PAICS (0.39) | PAICSKCNH2 | |
| SCHEMBL24220430 | 0.77 | PIM1 (0.44) | PAICSHDAC1 | |
| SCHEMBL20339051 | 0.77 | PAICS (0.55) | PAICS | |
| SCHEMBL24220398 | 0.77 | PAICS (0.61) | PAICSHDAC3KCNH2HDAC2 | |
| SCHEMBL24220397 | 0.76 | PAICS (0.47) | PAICSHDAC3KCNH2HDAC2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122549-A1 | OXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | LIFEARC (GB) | 2018-07-05 | — | — | WO | disclosed |