Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAICS | P22234 | 17/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20352042 | 0.88 | PAICS (0.40) | PAICSKCNH2 | |
| SCHEMBL21571638 | 0.81 | PAICS (0.50) | PAICS | |
| SCHEMBL20339077 | 0.80 | PAICS (0.49) | PAICS | |
| SCHEMBL20339064 | 0.79 | PAICS (0.39) | PAICSKCNH2 | |
| SCHEMBL21571661 | 0.79 | PAICS (0.53) | PAICS | |
| SCHEMBL21571640 | 0.79 | PAICS (0.42) | PAICSPOLB | |
| SCHEMBL21571657 | 0.79 | PAICS (0.53) | PAICS | |
| SCHEMBL20352101 | 0.79 | PAICS (0.49) | PAICS | |
| SCHEMBL20352118 | 0.79 | PAICS (0.54) | PAICSKCNH2 | |
| SCHEMBL21571645 | 0.78 | PAICS (0.55) | PAICS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3562824-B1 | OXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | LIFEARC (GB) | 2022-01-26 | — | — | EP | disclosed |