Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAICS | P22234 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 6/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20352034 | 0.77 | PAICS (0.59) | PAICS | |
| SCHEMBL24220558 | 0.70 | SMYD3 (0.33) | HTR6MAPT | |
| SCHEMBL20352120 | 0.69 | PAICS (0.49) | PAICS | |
| SCHEMBL21571665 | 0.69 | PAICS (0.49) | PAICS | |
| SCHEMBL20352138 | 0.68 | — | — | |
| SCHEMBL21579053 | 0.65 | PAICS (0.74) | PAICS | |
| SCHEMBL24220529 | 0.64 | PAICS (0.49) | PAICSHTR2A | |
| SCHEMBL24220472 | 0.62 | PAICS (0.58) | PAICS | |
| SCHEMBL20352032 | 0.62 | PAICS (0.58) | PAICS | |
| SCHEMBL20350506 | 0.62 | PAICS (0.44) | PAICSMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122549-A1 | OXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | LIFEARC (GB) | 2018-07-05 | — | — | WO | disclosed |