Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAICS | P22234 | 19/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24220491 | 0.88 | PAICS (0.42) | PAICSKCNH2 | |
| SCHEMBL24220536 | 0.88 | PAICS (0.43) | PAICS | |
| SCHEMBL20352103 | 0.86 | PAICS (0.53) | PAICS | |
| SCHEMBL20352094 | 0.85 | PAICS (0.37) | PAICSKCNH2 | |
| SCHEMBL20352120 | 0.85 | PAICS (0.49) | PAICSKCNH2 | |
| SCHEMBL21571641 | 0.84 | PAICS (0.43) | PAICS | |
| SCHEMBL21571640 | 0.82 | PAICS (0.42) | PAICS | |
| SCHEMBL24220473 | 0.82 | PAICS (0.38) | PAICSKCNH2 | |
| SCHEMBL20352062 | 0.82 | PAICS (0.38) | PAICS | |
| SCHEMBL24220529 | 0.81 | PAICS (0.49) | PAICSKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122549-A1 | OXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF CANCER | LIFEARC (GB) | 2018-07-05 | — | — | WO | disclosed |