Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 4/20 | 0.43 |
| ▸ | ANPEP | P15144 | 4/20 | 0.42 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.34 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22994945 | 0.84 | ANPEP (0.56) | ANPEPENPEPALDH1A1TDP1 | |
| SCHEMBL20342119 | 0.78 | ALDH1A1 (0.50) | KISS1RANPEPENPEPALDH1A1TDP1 | |
| SCHEMBL26864412 | 0.78 | ANPEP (0.45) | ANPEPENPEPALDH1A1TDP1 | |
| SCHEMBL25641484 | 0.78 | ALDH1A1 (0.50) | KISS1RANPEPENPEPALDH1A1TDP1 | |
| SCHEMBL24390485 | 0.78 | ANPEP (0.45) | ANPEPENPEPALDH1A1TDP1 | |
| SCHEMBL21991002 | 0.78 | ANPEP (0.45) | ANPEPENPEPALDH1A1TDP1 | |
| SCHEMBL17992778 | 0.78 | ALDH1A1 (0.50) | KISS1RANPEPENPEPALDH1A1TDP1 | |
| SCHEMBL16768817 | 0.77 | ANPEP (0.70) | ANPEPENPEPALDH1A1FOLH1 | |
| SCHEMBL25943327 | 0.77 | ANPEP (0.70) | ANPEPENPEPALDH1A1FOLH1 | |
| SCHEMBL25943328 | 0.75 | ANPEP (0.52) | ANPEPENPEPALDH1A1TDP1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3405477-B1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-06-07 | — | — | EP | disclosed |
| WO-2019201432-A1 | INHIBITORS OF BLOOD COAGULATION FACTOR XIII | ZEDIRA GMBH (DE) | 2019-10-24 | — | — | WO | disclosed |
| WO-2019202052-A1 | INHIBITORS OF BLOOD COAGULATION FACTOR XIII | ZEDIRA GMBH (DE) | 2019-10-24 | — | — | WO | disclosed |
| WO-2018122419-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2018-07-05 | — | — | WO | disclosed |