Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | PDE10A | Q9Y233 | 11/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21510705 | 0.89 | CYP1A2 (0.53) | CYP1A2CYP2D6CYP2C19PDE10AALDH1A1 | |
| SCHEMBL21859396 | 0.88 | CYP1A2 (0.53) | CYP1A2CYP2D6CYP2C19PDE10AALDH1A1 | |
| SCHEMBL19768724 | 0.87 | CYP1A2 (0.72) | CYP1A2CYP2D6CYP2C19PDE10AALDH1A1 | |
| SCHEMBL7783535 | 0.87 | CYP1A2 (0.51) | CYP1A2CYP2D6CYP2C19PDE10AALDH1A1 | |
| SCHEMBL11727575 | 0.87 | MAOA (0.56) | CYP1A2CYP2D6CYP2C19PDE10AALDH1A1 | |
| SCHEMBL17733428 | 0.87 | CYP1A2 (0.51) | CYP1A2CYP2D6CYP2C19PDE10AALDH1A1 | |
| SCHEMBL16806183 | 0.85 | CYP1A2 (0.66) | CYP1A2CYP2D6CYP2C19PDE10AALDH1A1 | |
| SCHEMBL10238647 | 0.85 | CYP1A2 (0.60) | CYP1A2CYP2D6CYP2C19PDE10AALDH1A1 | |
| SCHEMBL31236778 | 0.84 | CYP1A2 (0.68) | CYP1A2CYP2D6CYP2C19PDE10AALDH1A1 | |
| SCHEMBL25682892 | 0.83 | CYP1A2 (0.48) | CYP1A2CYP2D6CYP2C19PDE10AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222542-A1 | 5-AMINO-2-PIPERIDINON-3-YL-1-OXOISOINDOLINE DERIVATIVES FOR DEGRADATION OF IKZF2 DEGRADERS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2021-11-04 | — | — | WO | disclosed |
| WO-2021034081-A1 | ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME | 솔루스첨단소재 주식회사 | 2021-02-25 | — | — | WO | disclosed |
| US-20180186783-A1 | INHIBITORS OF PROTEIN KINASES | ALEXION PHARMACEUTICALS, INC. | 2018-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180186783-A1 | INHIBITORS OF PROTEIN KINASES | SYK, BTK, JAK1 | CYP1A2 1714/4885CYP2D6 2539/4885CYP2C19 1044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.