Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20354852 | 0.77 | AR (0.47) | CSNK2A2CSNK2BCSNK2A1ARHTR2A | |
| SCHEMBL26912582 | 0.77 | CSNK2A2 (0.33) | CSNK2A2CSNK2BCSNK2A1ARHTR2A | |
| SCHEMBL20355099 | 0.73 | CSNK2A2 (0.34) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL20354697 | 0.73 | IDO1 (0.38) | CSNK2A2CSNK2BCSNK2A1ARHTR2A | |
| SCHEMBL21569527 | 0.72 | CSNK2A2 (0.33) | CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL20355043 | 0.69 | GPR17 (0.34) | CSNK2A2CSNK2BCSNK2A1AR | |
| SCHEMBL26912879 | 0.68 | CSNK2A2 (0.50) | CSNK2A2CSNK2BCSNK2A1AR | |
| SCHEMBL26912618 | 0.67 | AURKA (0.38) | AR | |
| SCHEMBL8297157 | 0.67 | HTR2A (0.34) | HTR2AHTR2CHTR2B | |
| SCHEMBL28584478 | 0.62 | HTR2A (0.41) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122232-A1 | (AZA)INDOLE-, BENZOTHIOPHENE-, AND BENZOFURAN-3-SULFONAMIDES | UCB PHARMA GMBH (DE) | 2018-07-05 | — | — | WO | disclosed |