Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | TNF | P01375 | 7/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20355043 | 0.77 | GPR17 (0.34) | ARCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL20355101 | 0.77 | CSNK2A2 (0.33) | ARHTR2ACSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL31357976 | 0.77 | AR (0.47) | ARTNFRIPK1HTR2ARIPK3 | |
| SCHEMBL29958526 | 0.73 | TRIM24 (0.47) | ARTNFRIPK1HTR2ARIPK3 | |
| SCHEMBL17828249 | 0.73 | TRIM24 (0.47) | ARTNFRIPK1HTR2ARIPK3 | |
| SCHEMBL20354849 | 0.73 | AR (0.47) | ARTNFRIPK1HTR2ARIPK3 | |
| SCHEMBL20354697 | 0.73 | IDO1 (0.38) | ARHTR2ACSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL21569544 | 0.72 | TNF (0.45) | ARTNFRIPK1HTR2ARIPK3 | |
| SCHEMBL20053060 | 0.66 | TNF (0.62) | TNFRIPK1HTR2ARIPK3 | |
| SCHEMBL20354731 | 0.64 | GPR84 (0.58) | HTR2AGPR84DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018122232-A1 | (AZA)INDOLE-, BENZOTHIOPHENE-, AND BENZOFURAN-3-SULFONAMIDES | UCB PHARMA GMBH (DE) | 2018-07-05 | — | — | WO | disclosed |