Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.43 |
| ▸ | MEN1 | O00255 | 7/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.39 |
| ▸ | LMNA | P02545 | 6/20 | 0.37 |
| ▸ | HTT | P42858 | 6/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19497715 | 0.89 | CTSA (0.43) | MAPTKMT2AMEN1MAPK1KDM4E | |
| SCHEMBL15495199 | 0.89 | POLB (0.38) | MAPTKMT2AMEN1MAPK1KDM4E | |
| SCHEMBL19882271 | 0.87 | CTSA (0.41) | MAPTHTTPOLBAPEX1TDP1 | |
| SCHEMBL21558859 | 0.87 | POLB (0.36) | MAPTKMT2AMEN1MAPK1KDM4E | |
| SCHEMBL20275212 | 0.87 | POLB (0.36) | KMT2AMEN1HTTPOLBAPEX1 | |
| SCHEMBL18494395 | 0.86 | HTT (0.41) | MAPTKMT2AMEN1MAPK1KDM4E | |
| SCHEMBL18699599 | 0.86 | RARG (0.38) | MAPTKMT2AMEN1MAPK1KDM4E | |
| SCHEMBL20342951 | 0.86 | RARG (0.38) | MAPTKMT2AMEN1MAPK1KDM4E | |
| SCHEMBL21884772 | 0.86 | POLB (0.35) | HTTPOLBAPEX1TDP1CYP2C19 | |
| SCHEMBL29333473 | 0.86 | POLB (0.44) | MAPTKMT2AMEN1MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180188586-A1 | PROCESS OF PREPARING A LIGHT MODULATION ELEMENT | MERCK PATENT GMBH (DE) | 2018-07-05 | — | — | US | disclosed |