Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20355775 | 1.00 | POLB (0.44) | POLBAPEX1HTTTDP1GPR174 | |
| SCHEMBL15338837 | 0.88 | THRB (0.45) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL16559864 | 0.88 | POLB (0.43) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL15180381 | 0.88 | POLB (0.43) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL19497343 | 0.88 | POLB (0.43) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL20342982 | 0.86 | THRB (0.40) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL20355302 | 0.86 | MAPT (0.43) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL16559835 | 0.85 | POLB (0.43) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL21102080 | 0.85 | POLB (0.43) | POLBAPEX1HTTTDP1MAPT | |
| SCHEMBL16559814 | 0.85 | POLB (0.43) | POLBAPEX1HTTTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400561-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2024-07-17 | — | — | EP | disclosed |