Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3897267 | 0.91 | SMN1; SMN2 (0.60) | LMNASMN1; SMN2CNR1TDP1CA12 | |
| SCHEMBL1514666 | 0.84 | GAA (0.57) | LMNASMN1; SMN2CNR1TDP1CA12 | |
| SCHEMBL14424502 | 0.83 | TSHR (0.57) | LMNASMN1; SMN2CNR1TDP1CA12 | |
| SCHEMBL10272442 | 0.83 | TSHR (0.61) | LMNASMN1; SMN2CNR1TDP1CA12 | |
| SCHEMBL4373669 | 0.82 | CA12 (0.54) | CNR1CA12CA1CA2CA9 | |
| SCHEMBL13983936 | 0.81 | HSD17B10 (0.59) | SMN1; SMN2TDP1GAAKDM4EKMT2A | |
| SCHEMBL6078561 | 0.81 | HSD17B10 (0.66) | LMNASMN1; SMN2CA1CA2CA9 | |
| SCHEMBL1768478 | 0.81 | TSHR (0.52) | LMNASMN1; SMN2CNR1TDP1CA12 | |
| SCHEMBL1768474 | 0.81 | TSHR (0.52) | LMNASMN1; SMN2CNR1TDP1CA12 | |
| SCHEMBL992153 | 0.81 | SMN1; SMN2 (0.58) | LMNASMN1; SMN2TDP1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10654815-B2 | Urea compound and preparation method and application thereof | SHENZHEN CHIPSCREEN BIOSCIENCES CO., LTD. (CN) | 2020-05-19 | — | — | US | disclosed |
| CN-108250159-A | Carbamide compounds, preparation method and its application | 深圳微芯生物科技股份有限公司 | 2018-07-06 | — | — | CN | disclosed |
| WO-2018121560-A1 | UREA COMPOUND AND PREPARATION METHOD AND APPLICATION THEREOF | 深圳微芯生物科技有限责任公司 | 2018-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10654815-B2 | Urea compound and preparation method and application thereof | PDCD1, CD274, PDCD10 | LMNA 3041/4885SMN1; SMN2 3472/4885CNR1 1418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.