SCHEMBL3897267

SCHEMBL3897267

O=C(NCCN1CCOCC1)NCCN1CCOCC1

nearest known ligand 0.70

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.60
LMNA P02545 3/20 0.60
CNR1 P21554 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
CA12 O43570 1/20 0.59
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
CA9 Q16790 1/20 0.59
TSHR P16473 1/20 0.57
ALDH1A1 P00352 1/20 0.55
HTR1A P08908 1/20 0.55
MAOA P21397 1/20 0.55
MAOB P27338 1/20 0.55
KCNH2 Q12809 1/20 0.55
CD274 Q9NZQ7 1/20 0.55
KMT2A Q03164 1/20 0.55
GAA P10253 2/20 0.54
EPHX1 P07099 1/20 0.54
KDM4E B2RXH2 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1514666 0.93 GAA (0.57) SMN1; SMN2LMNACNR1TDP1CA12
SCHEMBL20356557 0.91 LMNA (0.54) SMN1; SMN2LMNACNR1TDP1CA12
SCHEMBL14424502 0.91 TSHR (0.57) SMN1; SMN2LMNACNR1TDP1CA12
SCHEMBL10272442 0.91 TSHR (0.61) SMN1; SMN2LMNACNR1TDP1CA12
SCHEMBL8280157 0.89 TDP1 (0.58) SMN1; SMN2LMNACNR1TDP1CA12
SCHEMBL26669381 0.89 SMN1; SMN2 (0.55) SMN1; SMN2LMNACNR1TDP1CA12
SCHEMBL2347336 0.88 GAA (0.70) SMN1; SMN2LMNATSHRALDH1A1GAA
SCHEMBL14237141 0.88 TDP1 (0.60) SMN1; SMN2LMNATDP1CA12CA1
SCHEMBL30522606 0.88 TDP1 (0.75) SMN1; SMN2LMNATDP1CA12CA1
SCHEMBL8070814 0.87 TDP1 (0.52) SMN1; SMN2LMNACNR1TDP1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9657129-B2 Cyclic amine compound and process for producing polyurethane resin by using it TOSOH CORPORATION (JP) 2017-05-23 US claimed
EP-2657237-B1 CYCLIC AMINE COMPOUND, AND PROCESS FOR PRODUCING POLYURETHANE RESIN USING SAME TOSOH CORP (JP) 2015-05-20 EP claimed
US-20130289232-A1 NOVEL CYCLIC AMINE COMPOUND AND PROCESS FOR PRODUCING POLYURETHANE RESIN BY USING IT TOSOH CORPORATION (JP) 2013-10-31 US claimed
EP-2657237-A1 NOVEL CYCLIC AMINE COMPOUND, AND PROCESS FOR PRODUCING POLYURETHANE RESIN USING SAME Tosoh Corporation (JP) 2013-10-30 EP claimed
EP-1443065-B1 Low acid organometallic catalyst for the production of flexible, semi-flexible and rigid polyurethane foams AIR PROD & CHEM (US) 2006-09-13 EP claimed
EP-1534766-A1 PROCESS FOR PREPARING POLYURETHANE FOAM GENERAL ELECTRIC COMPANY (US) 2005-06-01 EP claimed
US-6825238-B2 BISMUTH CARBOXYLATE OR BISMUTH SULFONATE HAVING LESS THAN 34% FREE ACID AS THE ORGANOMETALLIC CATALYST AIR PRODUCTS AND CHEMICALS, INC. 2004-11-30 US claimed
US-6818675-B2 USING REACTION PRODUCT OF TERTIARY AMINE AND ACID AS POLYMERIZATION CATALYST GENERAL ELECTRIC COMPANY 2004-11-16 US claimed
EP-0877042-B1 Reactive catalyst compositions for improving water blown polyurethane foam performance AIR PROD & CHEM (US) 2004-09-22 EP claimed
EP-1443065-A1 Low acid organometallic catalyst for the production of flexible, semi-flexible and rigid polyurethane foams AIR PRODUCTS AND CHEMICALS, INC. (US) 2004-08-04 EP claimed
US-20040147626-A1 LOW ACID ORGANOMETALLIC CATALYST FOR THE PRODUCTION OF FLEXIBLE, SEMI-FLEXIBLE AND RIGID POLYURETHANE FOAMS EVONIK DEGUSSA GMBH (DE) 2004-07-29 US claimed
WO-2004013201-A1 PROCESS FOR PREPARING POLYURETHANE FOAM GENERAL ELECTRIC COMPANY (US) 2004-02-12 WO claimed
US-20040029986-A1 Process for preparing polyurethane foam CROMPTON CORPORATION 2004-02-12 US claimed
EP-0877042-A1 Reactive catalyst compositions for improving water blown polyurethane foam performance AIR PRODUCTS AND CHEMICALS, INC. (US) 1998-11-11 EP claimed
EP-2787016-B1 Fast demold/extended cream time polyurethane formulations EVONIK DEGUSSA GMBH (DE) 2019-01-30 EP disclosed
EP-1534766-B2 PROCESS FOR PREPARING POLYURETHANE FOAM MOMENTIVE PERFORMANCE MAT INC (US) 2018-01-17 EP disclosed
US-9657129-B2 Cyclic amine compound and process for producing polyurethane resin by using it TOSOH CORPORATION (JP) 2017-05-23 US disclosed
WO-2004013201-A1 PROCESS FOR PREPARING POLYURETHANE FOAM GENERAL ELECTRIC COMPANY (US) 2004-02-12 WO disclosed
US-6232356-B1 INCREASING LOAD BEARING PROPERTIES OF POLYURETHANE FOAM USING UREA CATALYST AIR PRODUCTS AND CHEMICALS, INC. 2001-05-15 US disclosed
EP-0877042-A1 Reactive catalyst compositions for improving water blown polyurethane foam performance AIR PRODUCTS AND CHEMICALS, INC. (US) 1998-11-11 EP disclosed