Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | IDE | P14735 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 4/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.36 |
| ▸ | PARP1 | P09874 | 3/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.36 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20357415 | 0.87 | CYP1A2 (0.46) | L3MBTL1POLBGABRA5ALDH1A1IDE | |
| SCHEMBL18615681 | 0.85 | CACNB4 (0.43) | L3MBTL1RXFP1EPHX2 | |
| SCHEMBL18615769 | 0.78 | RXFP1 (0.41) | L3MBTL1RXFP1 | |
| Hydrochloric Acid SCHEMBL20357438 | 0.77 | RXFP1 (0.40) | L3MBTL1RXFP1 | |
| Hydrochloric Acid SCHEMBL20357435 | 0.77 | RXFP1 (0.40) | L3MBTL1RXFP1 | |
| SCHEMBL4963265 | 0.76 | EPHX2 (0.51) | EPHX2TNKSPARP2PARP1TNKS2 | |
| SCHEMBL4963257 | 0.76 | EPHX2 (0.51) | EPHX2TNKSPARP2PARP1TNKS2 | |
| Hydrochloric Acid SCHEMBL20357430 | 0.75 | EPHX2 (0.50) | EPHX2TNKSPARP2PARP1TNKS2 | |
| SCHEMBL18616063 | 0.73 | CYP1A2 (0.46) | GABRA5IDE | |
| SCHEMBL21853961 | 0.73 | TNKS (0.53) | EPHX2LDHATNKSPARP2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345893-B1 | UREA DERIVATIVE AND USE THEREFOR | TORAY INDUSTRIES (JP) | 2019-10-30 | — | — | EP | disclosed |
| US-10280145-B2 | Urea derivative and use therefor | TORAY INDUSTRIES, INC. (JP) | 2019-05-07 | — | — | US | disclosed |
| US-20180237398-A1 | UREA DERIVATIVE AND USE THEREFOR | TORAY INDUSTRIES, INC. (JP) | 2018-08-23 | — | — | US | disclosed |
| EP-3345893-A1 | UREA DERIVATIVE AND USE THEREFOR | Toray Industries, Inc. (JP) | 2018-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10280145-B2 | Urea derivative and use therefor | UTS2R, DDR1, WEE1 | L3MBTL1 1009/4885RXFP1 12/4885POLB 4268/4885 |
| US-20180237398-A1 | UREA DERIVATIVE AND USE THEREFOR | UTS2R, DDR1, WEE1 | L3MBTL1 1009/4885RXFP1 12/4885POLB 4268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.