Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 2/20 | 0.42 |
| ▸ | IDE | P14735 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.41 |
| ▸ | WNT1 | P04628 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20357206 | 0.87 | L3MBTL1 (0.46) | GABRA5IDEALDH1A1L3MBTL1CYP46A1 | |
| SCHEMBL18616063 | 0.86 | CYP1A2 (0.46) | CYP1A2CYP2C9CYP2C19CYP3A4KMT2A | |
| SCHEMBL20357315 | 0.82 | ABL1 (0.43) | HTTALDH1A1L3MBTL1WNT1DYRK1A | |
| SCHEMBL18616064 | 0.80 | CYP2A6 (0.45) | CYP1A2CYP2C9CYP2C19CYP3A4HTT | |
| Hydrochloric Acid SCHEMBL20357454 | 0.79 | CYP2A6 (0.44) | CYP1A2CYP2C9CYP2C19CYP3A4HTT | |
| Hydrochloric Acid SCHEMBL20357453 | 0.79 | CYP2A6 (0.44) | CYP1A2CYP2C9CYP2C19CYP3A4HTT | |
| SCHEMBL18615518 | 0.76 | ABL1 (0.46) | CYP1A2CYP2C9CYP2C19CYP3A4MAPT | |
| SCHEMBL20357380 | 0.76 | ABL1 (0.46) | CYP1A2CYP2C9CYP2C19CYP3A4MAPT | |
| SCHEMBL20357344 | 0.75 | ABL1 (0.46) | — | |
| SCHEMBL18615513 | 0.75 | ABL1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345893-B1 | UREA DERIVATIVE AND USE THEREFOR | TORAY INDUSTRIES (JP) | 2019-10-30 | — | — | EP | disclosed |
| US-10280145-B2 | Urea derivative and use therefor | TORAY INDUSTRIES, INC. (JP) | 2019-05-07 | — | — | US | disclosed |
| US-20180237398-A1 | UREA DERIVATIVE AND USE THEREFOR | TORAY INDUSTRIES, INC. (JP) | 2018-08-23 | — | — | US | disclosed |
| EP-3345893-A1 | UREA DERIVATIVE AND USE THEREFOR | Toray Industries, Inc. (JP) | 2018-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10280145-B2 | Urea derivative and use therefor | UTS2R, DDR1, WEE1 | CYP1A2 4745/4885CYP2C9 4544/4885CYP2C19 4354/4885 |
| US-20180237398-A1 | UREA DERIVATIVE AND USE THEREFOR | UTS2R, DDR1, WEE1 | CYP1A2 4745/4885CYP2C9 4544/4885CYP2C19 4354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.