Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 15/20 | 0.46 |
| ▸ | GPR6 | P46095 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | AADAC | P22760 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18615668 | 1.00 | EPHX2 (0.46) | EPHX2GPR6FAAHKDM4ETSHR | |
| SCHEMBL20357376 | 0.92 | EPHX2 (0.44) | EPHX2GPR6FAAHAADACGRM7 | |
| SCHEMBL18615472 | 0.92 | EPHX2 (0.44) | EPHX2GPR6FAAHAADACGRM7 | |
| SCHEMBL20976428 | 0.87 | GAA (0.39) | GPR6KDM4ETSHRNPSR1RAF1 | |
| SCHEMBL18615642 | 0.87 | EPHX2 (0.46) | EPHX2GPR6FAAHAADACRAF1 | |
| SCHEMBL18615475 | 0.87 | EPHX2 (0.41) | EPHX2GPR6FAAHAADACRAF1 | |
| SCHEMBL20357350 | 0.87 | EPHX2 (0.41) | EPHX2GPR6FAAHAADACRAF1 | |
| SCHEMBL20357331 | 0.87 | ALDH1A1 (0.39) | GPR6KDM4ETSHRNPSR1 | |
| SCHEMBL20357238 | 0.87 | EPHX2 (0.51) | EPHX2GPR6FAAHAADACRAF1 | |
| SCHEMBL18615510 | 0.87 | EPHX2 (0.51) | EPHX2GPR6FAAHAADACRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345893-B1 | UREA DERIVATIVE AND USE THEREFOR | TORAY INDUSTRIES (JP) | 2019-10-30 | — | — | EP | disclosed |
| US-10280145-B2 | Urea derivative and use therefor | TORAY INDUSTRIES, INC. (JP) | 2019-05-07 | — | — | US | disclosed |
| US-20180237398-A1 | UREA DERIVATIVE AND USE THEREFOR | TORAY INDUSTRIES, INC. (JP) | 2018-08-23 | — | — | US | disclosed |
| EP-3345893-A1 | UREA DERIVATIVE AND USE THEREFOR | Toray Industries, Inc. (JP) | 2018-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10280145-B2 | Urea derivative and use therefor | UTS2R, DDR1, WEE1 | EPHX2 4826/4885GPR6 1263/4885FAAH 4492/4885 |
| US-20180237398-A1 | UREA DERIVATIVE AND USE THEREFOR | UTS2R, DDR1, WEE1 | EPHX2 4826/4885GPR6 1263/4885FAAH 4492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.