SCHEMBL20357365

SCHEMBL20357365

CCN(CC)c1ccc(C(=O)c2ccc(C)cc2C(=O)O)c(O)c1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.76
L3MBTL1 Q9Y468 2/20 0.76
MEN1 O00255 2/20 0.76
KMT2A Q03164 2/20 0.76
ALDH1A1 P00352 11/20 0.58
KDM4E B2RXH2 6/20 0.58
GAA P10253 2/20 0.58
POLB P06746 1/20 0.58
CSNK2A1 P68400 1/20 0.47
MCL1 Q07820 3/20 0.44
MAPT P10636 6/20 0.43
RAB9A P51151 1/20 0.43
HPGD P15428 4/20 0.43
LMNA P02545 3/20 0.43
ALOX15 P16050 2/20 0.43
HSD17B10 Q99714 2/20 0.43
SLC16A3 O15427 1/20 0.43
SLC16A1 P53985 1/20 0.43
BCL2L1 Q07817 1/20 0.41
BLM P54132 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20357168 0.95 SMN1; SMN2 (0.76) SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL22938990 0.92 MEN1 (0.84) SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL9617192 0.89 MEN1 (0.79) SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL22939011 0.88 MEN1 (0.78) SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL20357130 0.87 ALDH1A1 (0.78) SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL29152906 0.87 MEN1 (0.69) SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL22938989 0.86 MEN1 (0.76) SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL11267085 0.86 SMN1; SMN2 (0.76) SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL39206 0.86 KMT2A (1.00) SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1
SCHEMBL22939653 0.85 MEN1 (0.77) SMN1; SMN2L3MBTL1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10435564-B2 Rhodamine-based colorant compound and process for producing same RIKEN (JP) 2019-10-08 US disclosed
US-20180244923-A1 RHODAMINE-BASED COLORANT COMPOUND AND PROCESS FOR PRODUCING SAME RIKEN (JP) 2018-08-30 US disclosed
EP-3345973-A1 RHODAMINE-BASED COLORANT COMPOUND AND PROCESS FOR PRODUCING SAME Riken (JP) 2018-07-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10435564-B2 Rhodamine-based colorant compound and process for producing same IK, RB1, HCCS SMN1; SMN2 4292/4885L3MBTL1 3734/4885MEN1 2744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.