SCHEMBL2035849

SCHEMBL2035849

CCc1ccc2c(c1)[CH]c1cc(CC)ccc1-2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
MAPK1 P28482 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
TRPA1 O75762 1/20 0.44
CYP2A6 P11509 2/20 0.43
CYP1A2 P05177 1/20 0.43
PDK2 Q15119 1/20 0.37
TP53 P04637 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
NOS3 P29474 1/20 0.35
NOS1 P29475 1/20 0.35
NOS2 P35228 1/20 0.35
KIF11 P52732 1/20 0.35
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27725019 0.91 ALDH1A1 (0.41) ALDH1A1NPC1RAB9ASMN1; SMN2LMNA
SCHEMBL3065370 0.89 ALDH1A1 (0.53) ALDH1A1NPC1RAB9ASMN1; SMN2LMNA
SCHEMBL4338325 0.89 NPC1 (0.40) ALDH1A1NPC1RAB9ASMN1; SMN2LMNA
SCHEMBL27383384 0.83 ALDH1A1 (0.47) ALDH1A1NPC1RAB9ASMN1; SMN2LMNA
SCHEMBL2051840 0.82 NPC1 (0.37) ALDH1A1NPC1RAB9ASMN1; SMN2LMNA
SCHEMBL2039542 0.81 CNR1 (0.52) PDK2LPLLIPGCA2
SCHEMBL2042974 0.80 ALDH1A1 (0.47) ALDH1A1NPC1RAB9ASMN1; SMN2LMNA
SCHEMBL2037494 0.78 SKP2 (0.48) ALDH1A1NPC1RAB9ASMN1; SMN2LMNA
SCHEMBL2047278 0.78 BCL2 (0.51) ALDH1A1NPC1RAB9ASMN1; SMN2LMNA
SCHEMBL28046784 0.76 ALDH1A1 (0.53) ALDH1A1NPC1RAB9ASMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5627247-A COMPOUNDS OF CYCLOPENTADIENE OR INDENE WITH FLUORENE AND GROUP IV METALS PHILLIPS PETROLEUM COMPANY (US) 1997-05-06 US claimed
CN-118202023-A Polypropylene viscosity modifier and lubricating oil thereof 埃克森美孚化学专利公司 2024-06-14 CN disclosed
US-11926802-B2 Lubricating oil composition with viscosity modifier based on syndiotactic propylene-based ethylene- propylene copolymers with improved properties EXXONMOBIL CHEMICAL PATENTS INC. (US) 2024-03-12 US disclosed
US-20230242745-A1 Process for Production of Thermoplastic Vulcanizates using Supported Catalyst Systems and Compositions Made Therefrom EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-08-03 US disclosed
US-20230174883-A1 LUBRICATING OIL COMPOSITION WITH VISCOSITY MODIFIER BASED ON SYNDIOTACTIC PROPYLENE-BASED ETHYLENE- PROPYLENE COPOLYMERS WITH IMPROVED PROPERTIES EXXONMOBIL CHEMICAL PATENTS INC. 2023-06-08 US disclosed
US-20230148328-A1 SYNDIOTACTIC PROPYLENE-BASED ETHYLENE- PROPYLENE COPOLYMERS EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-05-11 US disclosed
WO-2023081010-A1 POLYPROPYLENE VISCOSITY MODIFIERS AND LUBRICATING OILS THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-05-11 WO disclosed
CN-106661488-B Syndiotactic propylene polymers and lubricating oils containing the same 埃克森美孚化学专利公司 2021-04-09 CN disclosed
US-10876063-B2 Syndiotactic propylene polymers and lubricating oils comprising the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-12-29 US disclosed
EP-3174961-B1 SYNDIOTACTIC PROPYLENE POLYMERS AND LUBRICATING OILS COMPRISING THE SAME EXXONMOBIL CHEMICAL PATENTS INC (US) 2019-11-20 EP disclosed
US-7851569-B2 Rare earth metal complex, polymerization catalyst, and process for producing polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-12-14 US disclosed
US-20100261857-A1 OLEFIN/(METH)ACRYLATE BLOCK COPOLYMER AND METHOD FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-10-14 US disclosed
EP-2189483-A1 OLEFIN/(METH)ACRYLATE BLOCK COPOLYMER AND METHOD FOR PRODUCING THE SAME Sumitomo Chemical Company, Limited (JP) 2010-05-26 EP disclosed
US-7615660-B2 Production process of alkoxy-titanium complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-11-10 US disclosed
US-20090253875-A1 RARE EARTH METAL COMPLEX, POLYMERIZATION CATALYST AND METHOD FOR PRODUCING POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED 2009-10-08 US disclosed
EP-2045254-A1 RARE EARTH METAL COMPLEX, CATALYST FOR POLYMERIZATION AND PROCESS FOR PRODUCING POLYMER Sumitomo Chemical Company, Limited (JP) 2009-04-08 EP disclosed
US-20080306293-A1 Production Process of Alkoxy-Titanium Complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-12-11 US disclosed
EP-1845101-A1 METHOD FOR PRODUCING ALKOXYTITANIUM COMPLEX Sumitomo Chemical Company, Limited (JP) 2007-10-17 EP disclosed
CN-1169736-A Catalyst for olefin polymerization ASAHI CHEMICAL IND (JP) 1998-01-07 CN disclosed
US-5627247-A COMPOUNDS OF CYCLOPENTADIENE OR INDENE WITH FLUORENE AND GROUP IV METALS PHILLIPS PETROLEUM COMPANY (US) 1997-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080306293-A1 Production Process of Alkoxy-Titanium Complex ABL1, H1-10, ALK ALDH1A1 1690/4885NPC1 3893/4885RAB9A 312/4885
US-20090253875-A1 RARE EARTH METAL COMPLEX, POLYMERIZATION CATALYST AND METHOD FOR PRODUCING POLYMER RPS27L, LAS1L, AGL ALDH1A1 4278/4885NPC1 2833/4885RAB9A 3358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.