SCHEMBL203587

SCHEMBL203587

O=c1oc(-c2ccccc2)nc2cccc(F)c12

nearest known ligand 0.61

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ELANE P08246 6/20 0.61
C1R P00736 1/20 0.54
RAB9A P51151 4/20 0.50
MAPT P10636 4/20 0.50
NPC1 O15118 3/20 0.50
PBRM1 Q86U86 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
ALDH1A1 P00352 4/20 0.48
KDM4E B2RXH2 2/20 0.48
F2 P00734 2/20 0.48
KMT2A Q03164 3/20 0.47
HPGD P15428 1/20 0.47
LMNA P02545 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
MEN1 O00255 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
DHODH Q02127 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10344530 0.89 MAPT (0.54) ELANEC1RRAB9AMAPTNPC1
SCHEMBL10344798 0.87 HPN (0.57) ELANEC1RRAB9AMAPTNPC1
SCHEMBL17554052 0.84 ELANE (0.79) ELANEC1RRAB9AMAPTALDH1A1
SCHEMBL17554131 0.84 ELANE (0.72) ELANEC1RRAB9AMAPTNPC1
SCHEMBL11002682 0.84 F7 (0.53) ELANEC1RRAB9AMAPTNPC1
SCHEMBL10594678 0.84 PBRM1 (0.57) ELANEC1RRAB9AMAPTNPC1
SCHEMBL912739 0.84 F7 (0.58) ELANEC1RPBRM1
SCHEMBL6332256 0.83 ELANE (0.48) ELANEC1RRAB9AMAPTNPC1
SCHEMBL17554151 0.83 KDM4E (0.64) ELANERAB9AMAPTNPC1PBRM1
SCHEMBL7186075 0.82 F7 (0.54) ELANEC1RRAB9AMAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 662 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0136646-B1 PROCESS FOR THE PREPARATION OF 5-FLUOR-4H-3,1-BENZOXAZIN-4-ONES BASF Aktiengesellschaft (DE) 1989-01-25 EP claimed
US-4562254-A Preparation of 5-fluoro-2-phenyl-4H-3,1-benzoxazin-4-ones BASF AKTIENGESELLSCHAFT (DE) 1985-12-31 US claimed
EP-0136646-A2 Process for the preparation of 5-fluor-4H-3,1-benzoxazin-4-ones BASF Aktiengesellschaft (DE) 1985-04-10 EP claimed
EP-2170041-B2 ACTIVE INGREDIENT SUSPENSIONS IN GLYCERINE BAYER CROPSCIENCE AG (DE) 2020-12-23 EP disclosed
EP-3428148-B1 ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) 2020-07-08 EP disclosed
EP-3428148-A1 ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF Merial, Inc. (US) 2019-01-16 EP disclosed
EP-3088384-B1 ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF MERIAL INC (US) 2018-12-12 EP disclosed
US-9801374-B2 Active compound combinations comprising carboxamide derivatives BAYER CROPSCIENCE AG (DE) 2017-10-31 US disclosed
EP-2373157-B1 DISPERSIONS CONTAINING HYDROXYPHENYLPYRUVATE-DIOXYGENASE INHIBITORS BAYER IP GMBH (DE) 2017-08-16 EP disclosed
EP-2167473-B1 3-CYCLOPROPYL-4-(3-THIOBENZOYL)PYRAZOLES AND THEIR USE AS HERBICIDES BAYER IP GMBH (DE) 2017-07-05 EP disclosed
EP-3088384-A1 ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF Merial, Inc. (US) 2016-11-02 EP disclosed
EP-0121129-A1 2,5-Dihydro-5-arylimino-pyrroles, process for their production and their uses as herbicides BASF Aktiengesellschaft (DE) 1984-10-10 EP disclosed
EP-0120352-A1 Derivatives of N-acylanthranilic acids, process for their preparation and their use in combating weeds BASF Aktiengesellschaft (DE) 1984-10-03 EP disclosed
EP-0115808-A1 Cyclohexan-1,3-dione derivatives, process for their preparation and their use as herbicides BASF Aktiengesellschaft (DE) 1984-08-15 EP disclosed
EP-0104389-A2 Quinoline derivatives, process for their preparation and their use in the control of undesired plant growth BASF Aktiengesellschaft (DE) 1984-04-04 EP disclosed
US-4422864-A Cyclohexanedione derivatives, their preparation and herbicides containing them BASF AKTIENGESELLSCHAFT (DE) 1983-12-27 US disclosed
EP-0084665-A1 Thiadiazole derivatives, process for their preparation, and their use in combatting unwanted plant growth BASF Aktiengesellschaft (DE) 1983-08-03 EP disclosed
EP-0071707-A1 Cyclohexane-dione derivatives, process for their preparation and herbicides containing them BASF Aktiengesellschaft (DE) 1983-02-16 EP disclosed
EP-0070370-A1 Cyclohexane-dione derivatives, process for their preparation and herbicides containing them BASF Aktiengesellschaft (DE) 1983-01-26 EP disclosed
EP-0067382-A2 N-cyclohexyl-chloroacetamides, their preparation and their use in combating undesired plant growth BASF Aktiengesellschaft (DE) 1982-12-22 EP disclosed