SCHEMBL10344530

SCHEMBL10344530

O=c1oc(-c2ccc(F)cc2)nc2cccc(F)c12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.54
ELANE P08246 6/20 0.53
PBRM1 Q86U86 1/20 0.46
RAB9A P51151 4/20 0.46
NPC1 O15118 3/20 0.46
AR P10275 1/20 0.46
C1R P00736 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
ALDH1A1 P00352 3/20 0.44
USP1 O94782 1/20 0.43
USP19 O94966 1/20 0.43
UCHL3 P15374 1/20 0.43
TP53 P04637 2/20 0.43
KDM4E B2RXH2 2/20 0.43
LMNA P02545 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HSPD1 P10809 1/20 0.42
PTPN2 P17706 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL203587 0.89 ELANE (0.61) MAPTELANEPBRM1RAB9ANPC1
SCHEMBL11002682 0.86 F7 (0.53) MAPTELANEPBRM1RAB9ANPC1
SCHEMBL10344798 0.85 HPN (0.57) MAPTELANEPBRM1RAB9ANPC1
SCHEMBL10344640 0.85 ELANE (0.65) MAPTELANEPBRM1RAB9ANPC1
SCHEMBL17554151 0.85 KDM4E (0.64) MAPTELANEPBRM1RAB9ANPC1
SCHEMBL6332256 0.85 ELANE (0.48) MAPTELANEPBRM1RAB9ANPC1
SCHEMBL912739 0.83 F7 (0.58) ELANEPBRM1C1R
SCHEMBL10967915 0.83 NOTUM (0.47) MAPTELANEPBRM1RAB9ANPC1
SCHEMBL10344503 0.81 ELANE (0.47) MAPTELANEPBRM1RAB9ANPC1
SCHEMBL10594678 0.80 PBRM1 (0.57) MAPTELANEPBRM1RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0192111-B1 ISO-UREAS, PROCESSES FOR THEIR PRODUCTION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1990-05-16 EP disclosed
EP-0121129-B1 2,5-DIHYDRO-5-ARYLIMINO-PYRROLES, PROCESS FOR THEIR PRODUCTION AND THEIR USES AS HERBICIDES BASF Aktiengesellschaft (DE) 1989-02-01 EP disclosed
US-4726837-A Use of 4H-pyrido[2,3-d][1,3]oxazin-4-one derivatives for controlling undesirable plant growth BASF AKTIENGESELLSCHAFT (DE) 1988-02-23 US disclosed
US-4715889-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1987-12-29 US disclosed
US-4692187-A HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1987-09-08 US disclosed
US-4673740-A Preparation of substituted 2-phenyl-4H-3,1-benzoxazin-4-ones BASF AKTIENGESELLSCHAFT (DE) 1987-06-16 US disclosed
EP-0199276-A2 Process for preparaing substituted 2-phenyl-4H-3,1-benzoxazin-4-ones BASF Aktiengesellschaft (DE) 1986-10-29 EP disclosed
EP-0192111-A1 Iso-ureas, processes for their production and their use as herbicides BASF Aktiengesellschaft (DE) 1986-08-27 EP disclosed
EP-0115808-B1 CYCLOHEXAN-1,3-DIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES BASF Aktiengesellschaft (DE) 1986-08-20 EP disclosed
EP-0104389-B1 QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE CONTROL OF UNDESIRED PLANT GROWTH BASF Aktiengesellschaft (DE) 1986-07-16 EP disclosed
US-4585881-A 2,5-dihydro-5-aryliminopyrrole derivatives and their preparation BASF AKTIENGESELLSCHAFT (DE) 1986-04-29 US disclosed
EP-0170203-A2 4H-Pyrido(2,3-d)(1,3)oxazin-4-one derivatives, process for their preparation, and their use for combating undesired vegetation BASF Aktiengesellschaft (DE) 1986-02-05 EP disclosed
EP-0115808-A1 Cyclohexan-1,3-dione derivatives, process for their preparation and their use as herbicides BASF Aktiengesellschaft (DE) 1984-08-15 EP disclosed
EP-0104389-A2 Quinoline derivatives, process for their preparation and their use in the control of undesired plant growth BASF Aktiengesellschaft (DE) 1984-04-04 EP disclosed