Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.31 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678018 | 0.86 | TSHR (0.68) | TSHRALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL28441915 | 0.81 | TSHR (0.55) | TSHRALDH1A1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL8978071 | 0.81 | TSHR (0.88) | TSHRALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL2592667 | 0.78 | LMNA (0.42) | TSHRALDH1A1KDM4EMAPK1 | |
| SCHEMBL2832061 | 0.76 | TSHR (0.54) | TSHRALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL7121347 | 0.76 | TSHR (0.54) | TSHRALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL9645536 | 0.75 | TSHR (0.75) | TSHRALDH1A1SMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL2355275 | 0.75 | — | — | |
| SCHEMBL20262429 | 0.75 | TSHR (0.71) | TSHRALDH1A1SMN1; SMN2KDM4EMAPT | |
| SCHEMBL304813 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180196367-A1 | TONER AND METHOD OF PRODUCING TONER | CANON KABUSHIKI KAISHA (JP) | 2018-07-12 | — | — | US | disclosed |