Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8519393 | 0.95 | BCHE (0.63) | LMNAKMT2AMEN1SMN1; SMN2BCHE | |
| SCHEMBL2851912 | 0.83 | MAPK14 (0.64) | LMNAKMT2AMEN1SMN1; SMN2MTNR1A | |
| SCHEMBL5099006 | 0.83 | PDCD1 (0.65) | KMT2AMEN1BCHEMAOB | |
| SCHEMBL26633561 | 0.82 | BCHE (0.67) | LMNAKMT2AMEN1SMN1; SMN2MAPT | |
| SCHEMBL10133176 | 0.81 | NPC1 (0.67) | LMNAKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL17136480 | 0.81 | HDAC1 (0.65) | LMNAKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5098479 | 0.81 | BCHE (0.65) | KMT2AMEN1MTNR1AMTNR1BBCHE | |
| SCHEMBL97001 | 0.80 | KMT2A (0.68) | LMNAKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13652546 | 0.80 | LMNA (0.61) | LMNAKMT2AMEN1SMN1; SMN2ALDH1A1 | |
| Bromide SCHEMBL30703423 | 0.79 | KMT2A (0.66) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076784-A2 | NEW INHIBITORS OF CYCLOPHILINS AND USES THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2011-06-30 | — | — | WO | disclosed |