Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 17/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17075553 | 0.88 | AOC3 (0.65) | AOC3KCNH2 | |
| SCHEMBL20924303 | 0.87 | AOC3 (0.57) | AOC3KCNH2 | |
| SCHEMBL18976733 | 0.81 | AOC3 (0.59) | AOC3KCNH2 | |
| SCHEMBL18976775 | 0.80 | AOC3 (0.66) | AOC3KCNH2 | |
| SCHEMBL18976817 | 0.79 | AOC3 (0.55) | AOC3KCNH2 | |
| SCHEMBL2602381 | 0.78 | AOC3 (0.69) | AOC3KCNH2 | |
| SCHEMBL20924390 | 0.78 | AOC3 (0.61) | AOC3KCNH2 | |
| SCHEMBL20924382 | 0.78 | AOC3 (0.67) | AOC3KCNH2 | |
| SCHEMBL18976716 | 0.77 | AOC3 (0.67) | AOC3KCNH2 | |
| SCHEMBL22997056 | 0.77 | AOC3 (0.62) | AOC3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10428066-B2 | Imidazo[4,5-C]pyridine and pyrrolo[2,3-C]pyridine derivatives as SSAO inhibitors | PROXIMAGEN, LLC (US) | 2019-10-01 | — | — | US | disclosed |
| US-20180194763-A1 | IMIDAZO[4,5-C]PYRIDINE AND PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS SSAO INHIBITORS | PROXIMAGEN LIMITED (GB) | 2018-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10428066-B2 | Imidazo[4,5-C]pyridine and pyrrolo[2,3-C]pyridine derivatives as SSAO inhibitors | PNPO, SSB, XDH | AOC3 10/4885KCNH2 364/4885 |
| US-20180194763-A1 | IMIDAZO[4,5-C]PYRIDINE AND PYRROLO[2,3-C]PYRIDINE DERIVATIVES AS SSAO INHIBITORS | PNPO, SSB, XDH | AOC3 10/4885KCNH2 364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.