SCHEMBL20360758

SCHEMBL20360758

CNN(C)c1ccncn1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.37
SLC6A2 P23975 1/20 0.34
JAK2 O60674 1/20 0.34
JAK1 P23458 1/20 0.34
CHRM5 P08912 1/20 0.33
CHKA P35790 1/20 0.33
P2RX7 Q99572 1/20 0.32
CYP3A4 P08684 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1321225 0.78
SCHEMBL30775432 0.78
SCHEMBL22931659 0.78 HSP90AA1 (0.42) HSP90AA1SLC6A2JAK2JAK1CHRM5
Hydrochloric Acid SCHEMBL9529929 0.76 CHRM5 (0.42) HSP90AA1SLC6A2JAK2JAK1CHRM5
SCHEMBL11257271 0.74
SCHEMBL767099 0.73
SCHEMBL30775420 0.71 SLC6A2 (0.43) HSP90AA1SLC6A2CHRM5CHKAP2RX7
SCHEMBL14344891 0.71 SLC6A2 (0.43) HSP90AA1SLC6A2CHRM5CHKAP2RX7
SCHEMBL6248536 0.69 HSP90AA1 (0.35) HSP90AA1SLC6A2P2RX7
SCHEMBL2104942 0.69 SLC6A2 (0.39) HSP90AA1SLC6A2JAK2JAK1CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118355118-A Compositions and methods for treating alpha-1 antitrypsin deficiency 英特利亚治疗股份有限公司 2024-07-16 CN disclosed
CN-118302540-A Methods and systems including cassettes for sequencing target polynucleotides DNAE诊断有限公司 2024-07-05 CN disclosed
CN-117925623-B Compositions for HAO1 gene editing and treatment of PH1 北京引正基因科技有限公司 2024-06-07 CN disclosed
CN-117980482-A Genome editing of RBM20 mutations 德克萨斯大学系统董事会 2024-05-03 CN disclosed
CN-117940153-A Programmed cell death protein 1 (PD 1) compositions and methods for cell-based therapies 因特利亚治疗公司 2024-04-26 CN disclosed
CN-117925623-A Compositions for HAO1 gene editing and treatment of PH1 北京引正基因科技有限公司 2024-04-26 CN disclosed
CN-117737062-A Compositions and methods for treating alpha-1 antitrypsin deficiency 因特利亚治疗公司 2024-03-22 CN disclosed
CN-110382697-B Compositions and methods for treating alpha-1 antitrypsin deficiency 因特利亚治疗公司 2023-12-29 CN disclosed
CN-117280024-A Polynucleotides, compositions and methods for genome editing involving deamination 因特利亚治疗公司 2023-12-22 CN disclosed
CN-117098840-A Natural killer cell receptor 2B4 compositions and methods for immunotherapy 因特利亚治疗公司 2023-11-21 CN disclosed
CN-105209639-A Method for amplifying nucleic acid on solid phase carrier ARNOLD LYLE J 2015-12-30 CN disclosed
CN-105209640-A Method for amplifying nucleic acid using hairpin oligonucleotide ARNOLD LYLE J 2015-12-30 CN disclosed
CN-104884638-A Compositions and methods for detecting human papillomavirus nucleic acids GEN PROBE INC 2015-09-02 CN disclosed
CN-104755630-A Multiphase nucleic acid amplification GEN PROBE INC 2015-07-01 CN disclosed
CN-102985566-B Method and apparatus for identifying analyte-containing samples using a single read determination of analyte and process control signal GEN PROBE INC 2015-06-17 CN disclosed
CN-104619622-A Systems, methods, and apparatus for automated incubation GEN PROBE INC 2015-05-13 CN disclosed
CN-104169438-A Asymmetric hairpin target capture oligomers GEN PROBE INC 2014-11-26 CN disclosed
CN-102985566-A Method and apparatus for identifying analyte-containing samples using a single read determination of analyte and process control signal GEN PROBE INC 2013-03-20 CN disclosed
CN-1398301-B Method for labeling nucleic acid BIO MERIEUX 2011-03-23 CN disclosed
CN-1398301-A Method for labeling nucleic acid BIO MERIEUX (FR) 2003-02-19 CN disclosed