⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1321225 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL9529929 | 0.98 | CHRM5 (0.42) | — | |
| Pyridine SCHEMBL27648110 | 0.89 | CHRM5 (0.41) | — | |
| SCHEMBL22931659 | 0.85 | HSP90AA1 (0.42) | — | |
| SCHEMBL11257271 | 0.81 | — | — | |
| SCHEMBL14344891 | 0.78 | SLC6A2 (0.43) | — | |
| SCHEMBL20360758 | 0.78 | HSP90AA1 (0.37) | — | |
| SCHEMBL30775420 | 0.78 | SLC6A2 (0.43) | — | |
| SCHEMBL2104942 | 0.76 | SLC6A2 (0.39) | — | |
| SCHEMBL767099 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12240836-B2 | Compounds as GCN2 inhibitors, pharmaceutical compositions and uses thereof | DONG-A ST CO., LTD. (KR) | 2025-03-04 | — | — | US | disclosed |
| US-20240025884-A1 | COMPOUNDS AS GCN2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | DONG-A ST CO., LTD. (KR) | 2024-01-25 | — | — | US | disclosed |