Eugenol

Eugenol

SCHEMBL20361

C=CCc1ccc(O)c(OC)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 1.00
ALOX5 P09917 2/20 1.00
PTGS1 P23219 2/20 1.00
TRPM8 Q7Z2W7 2/20 1.00
CYP3A4 P08684 1/20 1.00
AR P10275 1/20 1.00
GABRA1 P14867 3/20 0.71
GABRB2 P47870 3/20 0.71
PPARG P37231 2/20 0.71
PPARD Q03181 2/20 0.71
PPARA Q07869 1/20 0.71
XDH P47989 1/20 0.61
CNR2 P34972 2/20 0.61
KDM4E B2RXH2 2/20 0.59
MEN1 O00255 2/20 0.59
GAA P10253 2/20 0.59
MAPT P10636 2/20 0.59
KMT2A Q03164 2/20 0.59
ALDH2 P05091 1/20 0.59
AKR1B1 P15121 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Eugenol SCHEMBL29364978 1.00 ALDH1A1 (1.00) ALDH1A1ALOX5PTGS1TRPM8CYP3A4
Eugenol SCHEMBL788240 1.00 ALDH1A1 (1.00) ALDH1A1ALOX5PTGS1TRPM8CYP3A4
Eugenol SCHEMBL29126189 1.00 ALDH1A1 (1.00) ALDH1A1ALOX5PTGS1TRPM8CYP3A4
Eugenol SCHEMBL25377864 0.98 ALDH1A1 (0.97) ALDH1A1ALOX5PTGS1TRPM8CYP3A4
Eugenol SCHEMBL9016998 0.98 ALDH1A1 (0.97) ALDH1A1ALOX5PTGS1TRPM8CYP3A4
Eugenol SCHEMBL21114900 0.98 ALDH1A1 (0.97) ALDH1A1ALOX5PTGS1TRPM8CYP3A4
Eugenol SCHEMBL5030243 0.98 ALDH1A1 (0.97) ALDH1A1ALOX5PTGS1TRPM8CYP3A4
Eugenol SCHEMBL5689917 0.98 ALDH1A1 (0.97) ALDH1A1ALOX5PTGS1TRPM8CYP3A4
Eugenol SCHEMBL31168047 0.98 ALDH1A1 (0.97) ALDH1A1ALOX5PTGS1TRPM8CYP3A4
Eugenol SCHEMBL30378957 0.98 ALDH1A1 (0.97) ALDH1A1ALOX5PTGS1TRPM8CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 97397 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144725-A1 TOOTH DESENSITIZING ORAL CARE COMPOSITIONS, DEVICES, AND METHODS THE PROCTER & GAMBLE COMPANY (US) 2026-05-28 US claimed
EP-4289275-B1 INSECT REPELLENT COMPOSITION UNIV WIEN BODENKULTUR (AT) 2026-05-27 EP claimed
EP-4746862-A2 ENHANCED DELIVERY EPINEPHRINE AND PRODRUG COMPOSITIONS Aquestive Therapeutics, Inc. (US) 2026-05-27 EP claimed
EP-4746708-A1 VOC COMPOSITION AND MINERAL CARRIER THEREOF Agriodor (FR) 2026-05-27 EP claimed
US-12635710-B2 Methods of using formaldehyde-free antimicrobial compositions in animal by-product compositions EASTMAN CHEMICAL COMPANY (US) 2026-05-26 US claimed
CN-122080524-A Anti-yellowing antibacterial composite material particle and preparation method thereof 2026-05-26 CN claimed
CN-122075448-A Pharmaceutical composition with enhanced permeation 2026-05-26 CN claimed
CN-122082144-A Preparation method of light-triggered slow-release type traditional Chinese medicine antibacterial mosquito-proof outdoor textile and product thereof 2026-05-26 CN claimed
CN-122075454-A Smell composition for improving non-motor symptoms of parkinsonism, multi-layer controlled release olfactory training component and preparation method thereof 2026-05-26 CN claimed
CN-116965448-B Natural food preservative composition and application thereof Jinjiang Licheng Food Technology Co.,Ltd. (CN) 2026-05-26 CN claimed
US-4053657-A FOODS AND FLAVOR USE OF 1-(3,3-DIMETHYL-2-NORBORNYL-2-PROPANONE INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1977-10-11 US claimed
US-4040970-A WITH COPOLYMER FOR RENDERING THE TONER NEGATIVELY CHARGEABLE CANON KABUSHIKI KAISHA (JA) 1977-08-09 US claimed
US-4041005-A AN ADMIXTURE WITH AN ESSENTIAL OIL THE STANDARD OIL COMPANY (US) 1977-08-09 US claimed
US-RE29298-E Deposition of vaporized flavorant on tobacco BROWN & WILLIAMSON TOBACCO CORPORATION (US) 1977-07-12 US claimed
US-4000329-A Flavoring compositions and foods containing one or more alkyl side chain methyl substituted or unsubstituted 2,2,6-trimethyl-1-cyclohexen-1-vinyl alkanoates INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 1976-12-28 US claimed
US-3994838-A Poly(phosphazene) vulcanizates and foams HORIZONS INCORPORATED, A DIVISION OF HORIZONS RESEARCH INCORPORATED (US) 1976-11-30 US claimed
US-3949071-A DIETHYL ETHER; EUGENOL; CHLOROPHYLL, 1A METAL CARBONATE; FATTY ACID; ANIONIC SURFACTANT FERRATON AKTIESELSKAB (DK) 1976-04-06 US claimed
US-3947570-A MOUTHWASH, LEMON OIL COLGATE-PALMOLIVE COMPANY (US) 1976-03-30 US claimed
US-3944679-A Process for imparting a coumarin-like aroma and flavor to tobacco, foods and drinks THE JAPAN TOBACCO & SALT PUBLIC CORPORATION (JA) 1976-03-16 US claimed
US-3943267-A Method of remineralizing and immunizing tooth enamel for the prevention and control of tooth decay and dental caries Randol, Neil J. (US) 1976-03-09 US claimed