Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK2 | Q13002 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18361177 | 0.96 | GRIK2 (0.42) | GRIK2PPARGAKR1C3AKR1C2KDM4E | |
| SCHEMBL18361181 | 0.91 | METAP2 (0.39) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL20364439 | 0.89 | GRIK2 (0.38) | GRIK2PPARGAKR1C3AKR1C2KDM4E | |
| SCHEMBL20364437 | 0.87 | AKR1C3 (0.42) | PPARGAKR1C3AKR1C2KDM4EHPGD | |
| SCHEMBL18361173 | 0.85 | PPARG (0.41) | GRIK2PPARGAKR1C3AKR1C2KDM4E | |
| SCHEMBL20364438 | 0.85 | PPARG (0.43) | GRIK2PPARGAKR1C3AKR1C2KDM4E | |
| SCHEMBL20364440 | 0.83 | AKR1C3 (0.36) | PPARGAKR1C3AKR1C2KDM4EHPGD | |
| SCHEMBL18361118 | 0.83 | GRIK2 (0.39) | GRIK2PPARGAKR1C3AKR1C2KDM4E | |
| SCHEMBL20364446 | 0.82 | GRIK2 (0.38) | GRIK2KDM4EHPGDMAPTHTT | |
| SCHEMBL18361165 | 0.80 | METAP2 (0.39) | PPARGMAPTALDH1A1L3MBTL1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180198075-A1 | ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES | SAMSUNG DISPLAY CO., LTD. (KR) | 2018-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180198075-A1 | ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES | C1R, ORC3, OR10J3 | GRIK2 2880/4885PPARG 4560/4885AKR1C3 110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.