Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12371398 | 0.94 | MAPT (0.42) | MAPTTHRBPSMB8PSMB5POLB | |
| SCHEMBL23506444 | 0.82 | MAPT (0.41) | MAPTTHRBPOLBTP53KDM4E | |
| SCHEMBL23471909 | 0.81 | KDM4E (0.53) | MAPTTHRBTP53KDM4EALDH1A1 | |
| SCHEMBL1985951 | 0.77 | POLB (0.53) | POLBSLC26A3CA12CA9 | |
| SCHEMBL18882648 | 0.77 | POLB (0.42) | MAPTPOLBTP53KDM4EALDH1A1 | |
| SCHEMBL18041269 | 0.77 | POLB (0.42) | MAPTPOLBTP53KDM4EALDH1A1 | |
| SCHEMBL20364733 | 0.76 | KDM4E (0.53) | MAPTTHRBPSMB8PSMB5KDM4E | |
| SCHEMBL16645386 | 0.73 | KDM4E (0.56) | MAPTPOLBTP53KDM4EALDH1A1 | |
| SCHEMBL18807744 | 0.72 | KDM4E (0.43) | MAPTPOLBKDM4EALDH1A1HPGD | |
| SCHEMBL23480242 | 0.72 | CYP2D6 (0.40) | MAPTTHRBPSMB8PSMB5TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180196033-A1 | CELL TRACKING REAGENTS AND THEIR METHODS OF USE | Life Technologies Corporation | 2018-07-12 | — | — | US | disclosed |