Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GLA | P06280 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20364734 | 0.94 | MAPT (0.40) | MAPTTHRBPSMB8PSMB5TP53 | |
| SCHEMBL23506444 | 0.86 | MAPT (0.41) | MAPTTHRBTP53POLBKDM4E | |
| SCHEMBL23471909 | 0.84 | KDM4E (0.53) | MAPTTHRBTP53KDM4EALDH1A1 | |
| SCHEMBL1985951 | 0.81 | POLB (0.53) | POLBSLC26A3 | |
| SCHEMBL18041269 | 0.81 | POLB (0.42) | MAPTTP53POLBKDM4EALDH1A1 | |
| SCHEMBL18882648 | 0.81 | POLB (0.42) | MAPTTP53POLBKDM4EALDH1A1 | |
| SCHEMBL23480242 | 0.77 | CYP2D6 (0.40) | MAPTTHRBPSMB8PSMB5TP53 | |
| SCHEMBL16645386 | 0.76 | KDM4E (0.56) | MAPTTP53POLBKDM4EALDH1A1 | |
| SCHEMBL18807744 | 0.75 | KDM4E (0.43) | MAPTPOLBKDM4EALDH1A1GLA | |
| SCHEMBL22030047 | 0.75 | PSMB8 (0.54) | MAPTTHRBPSMB8PSMB5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3314257-B1 | CELL TRACKING REAGENTS AND THEIR METHODS OF USE | LIFE TECHNOLOGIES CORP (US) | 2021-06-16 | — | — | EP | disclosed |
| EP-3174953-B1 | ENVIRONMENTALLY RESPONSIVE CHROMATIC LUMINESCENT COMPOSITIONS WITH IMPROVED HAND | BAMBU VAULT LLC (US) | 2020-09-02 | — | — | EP | disclosed |
| US-20200188535-A1 | Bioorthogonal Turn-on Probes | THE GENERAL HOSPITAL CORPORATION | 2020-06-18 | — | — | US | disclosed |
| US-20180196033-A1 | CELL TRACKING REAGENTS AND THEIR METHODS OF USE | Life Technologies Corporation | 2018-07-12 | — | — | US | disclosed |
| US-20180196033-A1 | CELL TRACKING REAGENTS AND THEIR METHODS OF USE | Life Technologies Corporation | 2018-07-12 | — | — | US | disclosed |
| EP-3174953-A1 | ENVIRONMENTALLY RESPONSIVE CHROMIC LUMINESCENT MATERIALS WITH IMPROVED HAND | Performance Indicator, LLC (US) | 2017-06-07 | — | — | EP | disclosed |
| US-20160121002-A1 | Bioorthogonal Turn-on Probes | THE GENERAL HOSPITAL CORPORATION (US) | 2016-05-05 | — | — | US | disclosed |
| US-20160121002-A1 | Bioorthogonal Turn-on Probes | THE GENERAL HOSPITAL CORPORATION (US) | 2016-05-05 | — | — | US | disclosed |
| WO-2016019100-A1 | ENVIRONMENTALLY RESPONSIVE CHROMIC LUMINESCENT MATERIALS WITH IMPROVED HAND | PERFORMANCE INDICATOR, LLC (US) | 2016-02-04 | — | — | WO | disclosed |
| US-8003394-B2 | Methods for metal assays using optical techniques | AJJER LLC (US) | 2011-08-23 | — | — | US | disclosed |
| US-8003394-B2 | Methods for metal assays using optical techniques | AJJER LLC (US) | 2011-08-23 | — | — | US | disclosed |
| US-20100035351-A1 | Methods for metal assays using optical techniques | AJJER LLC | 2010-02-11 | — | — | US | disclosed |
| US-20100035351-A1 | Methods for metal assays using optical techniques | AJJER LLC | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160121002-A1 | Bioorthogonal Turn-on Probes | MPI, TIPRL, BAZ1A | MAPT 1276/4885THRB 474/4885PSMB8 3728/4885 |
| US-20200188535-A1 | Bioorthogonal Turn-on Probes | ZYX, MPI, BAZ1A | MAPT 870/4885THRB 392/4885PSMB8 3624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.