Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RRM1 | P23921 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14444028 | 0.92 | POLB (0.55) | MMP2POLBCA12CA2CA9 | |
| SCHEMBL30889119 | 0.91 | MMP2 (0.67) | MMP2POLBKMT2ACYP2D6CYP2C9 | |
| SCHEMBL16965176 | 0.86 | POLB (0.52) | MMP2POLBCA12CA2CA9 | |
| SCHEMBL30120748 | 0.85 | MMP2 (0.56) | MMP2KMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3583374 | 0.85 | MMP2 (0.56) | MMP2KMT2ACYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8054823 | 0.85 | POLB (0.55) | MMP2POLBCA12CA2CA9 | |
| SCHEMBL14861105 | 0.85 | CA12 (0.61) | POLBCA12CA2KMT2A | |
| SCHEMBL6961215 | 0.85 | CA12 (0.61) | POLBCA12CA2KMT2A | |
| SCHEMBL19710389 | 0.85 | POLB (0.55) | MMP2POLBCA12CA2CA9 | |
| SCHEMBL13073331 | 0.85 | CA12 (0.61) | POLBCA12CA2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018128826-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS | CIDARA THERAPEUTICS, INC. (US) | 2018-07-12 | — | — | WO | disclosed |