Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8838006 | 0.88 | GNAI3 (0.54) | HTR2CHSD17B10ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL12574191 | 0.80 | GNAI3 (0.51) | HTR2CALDH1A1KDM4ESMN1; SMN2GNAI3 | |
| SCHEMBL3935665 | 0.80 | GNAI3 (0.51) | HTR2CALDH1A1KDM4ESMN1; SMN2GNAI3 | |
| SCHEMBL15082268 | 0.79 | HTR2C (0.44) | HTR2CALDH1A1KDM4ESMN1; SMN2GNAI3 | |
| Hydrochloric Acid SCHEMBL2015546 | 0.79 | GNAI3 (0.54) | HTR2CALDH1A1KDM4ESMN1; SMN2GNAI3 | |
| Hydrochloric Acid SCHEMBL2015550 | 0.79 | GNAI3 (0.54) | HTR2CALDH1A1KDM4ESMN1; SMN2GNAI3 | |
| SCHEMBL4635091 | 0.78 | SMN1; SMN2 (0.47) | HTR2CHSD17B10ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9961298 | 0.77 | HSD17B10 (0.53) | HSD17B10ALDH1A1KDM4ESMN1; SMN2EPHX2 | |
| SCHEMBL14534815 | 0.77 | HSD17B10 (0.58) | HSD17B10ALDH1A1KDM4ESMN1; SMN2EPHX2 | |
| SCHEMBL24025461 | 0.77 | SMN1; SMN2 (0.46) | HTR2CHSD17B10ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018128826-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS | CIDARA THERAPEUTICS, INC. (US) | 2018-07-12 | — | — | WO | disclosed |