Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 18/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL896863 | 0.81 | ALK (0.70) | ALK | |
| SCHEMBL896858 | 0.81 | ALK (0.70) | ALK | |
| SCHEMBL896861 | 0.81 | ALK (0.70) | ALK | |
| SCHEMBL898333 | 0.79 | ALK (0.82) | ALK | |
| SCHEMBL898330 | 0.79 | ALK (0.82) | ALK | |
| SCHEMBL898332 | 0.79 | ALK (0.82) | ALK | |
| SCHEMBL21443207 | 0.72 | ALK (0.71) | ALK | |
| SCHEMBL20004260 | 0.72 | ALK (0.71) | ALK | |
| SCHEMBL1756013 | 0.71 | ALK (0.77) | ALK | |
| SCHEMBL20004258 | 0.70 | ALK (0.68) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613729-A1 | TETRACYCLIC COMPOUNDS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2020-02-26 | — | — | EP | disclosed |
| EP-3345903-A1 | TETRACYCLIC COMPOUNDS | Chugai Seiyaku Kabushiki Kaisha (JP) | 2018-07-11 | — | — | EP | disclosed |