Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 7/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPY4R | P50391 | 3/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21227687 | 0.86 | ALDH1A1 (0.41) | MAP2K1POLBGAATDP1RAB9A | |
| SCHEMBL12602979 | 0.83 | SMN1; SMN2 (0.42) | MAP2K1POLBGAATDP1BRD4 | |
| SCHEMBL21227681 | 0.82 | GAA (0.43) | POLBGAAMEN1KMT2ANPY4R | |
| SCHEMBL24374804 | 0.82 | HIF1A (0.50) | POLBTDP1MEN1RAB9AKMT2A | |
| SCHEMBL16342388 | 0.80 | BRD4 (0.46) | GAAMEN1KMT2ABRD4NPSR1 | |
| SCHEMBL12602996 | 0.80 | BTK (0.46) | POLBGAATDP1MEN1KMT2A | |
| SCHEMBL16651233 | 0.79 | CNR2 (0.41) | RAB9ABRD4RXFP1 | |
| SCHEMBL16651308 | 0.78 | BRD4 (0.36) | MAP2K1BRD4 | |
| SCHEMBL16342375 | 0.77 | AAK1 (0.43) | GAAKMT2AGPR35BRD4RXFP1 | |
| SCHEMBL22631630 | 0.76 | MALT1 (0.49) | MEN1KMT2ANPY4RGPR35RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10023592-B2 | Bromodomain inhibitors | CELGENE QUANTICEL RESEARCH, INC. (US) | 2018-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10023592-B2 | Bromodomain inhibitors | BRD3, EP300, BRPF3 | MAP2K1 1407/4885POLB 586/4885GAA 2844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.