Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | ATM | Q13315 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11929320 | 0.89 | CYP3A4 (0.76) | CYP2C9CYP3A4KDM4EHPGDATM | |
| Althiazide SCHEMBL29388917 | 0.84 | CYP3A4 (1.00) | CYP2C9CYP3A4KDM4EHPGDATM | |
| Althiazide SCHEMBL26514792 | 0.84 | CYP3A4 (1.00) | CYP2C9CYP3A4KDM4EHPGDATM | |
| Althiazide SCHEMBL25992937 | 0.84 | CYP3A4 (1.00) | CYP2C9CYP3A4KDM4EHPGDATM | |
| Althiazide SCHEMBL124525 | 0.84 | CYP3A4 (1.00) | CYP2C9CYP3A4KDM4EHPGDATM | |
| SCHEMBL23721761 | 0.77 | CYP2C9 (0.69) | CYP2C9CYP3A4KDM4EHPGDATM | |
| SCHEMBL11929014 | 0.75 | LMNA (0.69) | CYP2C9CYP3A4KDM4EHPGDATM | |
| SCHEMBL20369162 | 0.74 | LMNA (0.46) | CYP2C9CYP3A4KDM4EHPGDATM | |
| SCHEMBL10539700 | 0.72 | KDM4E (0.73) | CYP2C9CYP3A4KDM4EHPGDATM | |
| Epithiazide SCHEMBL124824 | 0.68 | CYP3A4 (0.71) | CYP2C9CYP3A4KDM4EHPGDATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180194732-A1 | MULTI-API LOADING PRODRUGS | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2018-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180194732-A1 | MULTI-API LOADING PRODRUGS | AADAC, PAICS, ABCG2 | CYP2C9 30/4885CYP3A4 69/4885KDM4E 423/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.