Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 10/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CCKAR | P32238 | 3/20 | 0.37 |
| ▸ | CCKBR | P32239 | 3/20 | 0.37 |
| ▸ | RAF1 | P04049 | 2/20 | 0.33 |
| ▸ | BRAF | P15056 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20370071 | 1.00 | CBLB (0.38) | CBLBKDM4EALDH1A1HPGDCCKAR | |
| SCHEMBL20369606 | 0.89 | KDM4E (0.37) | CBLBKDM4EALDH1A1HPGDCCKAR | |
| SCHEMBL20369895 | 0.89 | KDM4E (0.37) | CBLBKDM4EALDH1A1HPGDCCKAR | |
| SCHEMBL20369894 | 0.89 | KDM4E (0.37) | CBLBKDM4EALDH1A1HPGDCCKAR | |
| SCHEMBL20867088 | 0.88 | CCKAR (0.50) | CBLBCCKARCCKBR | |
| SCHEMBL20867031 | 0.88 | CCKAR (0.50) | CBLBCCKARCCKBR | |
| SCHEMBL20866784 | 0.85 | NOTCH1 (0.42) | CBLBKDM4EALDH1A1HPGDCCKAR | |
| SCHEMBL20866782 | 0.85 | NOTCH1 (0.42) | CBLBKDM4EALDH1A1HPGDCCKAR | |
| SCHEMBL20866783 | 0.85 | NOTCH1 (0.42) | CBLBKDM4EALDH1A1HPGDCCKAR | |
| SCHEMBL20369949 | 0.84 | CBLB (0.42) | CBLBKDM4EALDH1A1HPGDCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018129287-A1 | HETEROARYLDIAZEPINE DERIVATIVES AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2018-07-12 | — | — | WO | disclosed |