Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTCH1 | P46531 | 12/20 | 0.42 |
| ▸ | RBPJ | Q06330 | 6/20 | 0.42 |
| ▸ | CCKAR | P32238 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 1/20 | 0.39 |
| ▸ | CBLB | Q13191 | 6/20 | 0.38 |
| ▸ | NOTCH3 | Q9UM47 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20866783 | 1.00 | NOTCH1 (0.42) | NOTCH1RBPJCCKARCCKBRCBLB | |
| SCHEMBL20866784 | 1.00 | NOTCH1 (0.42) | NOTCH1RBPJCCKARCCKBRCBLB | |
| SCHEMBL20867088 | 0.90 | CCKAR (0.50) | CCKARCCKBRCBLB | |
| SCHEMBL20867031 | 0.90 | CCKAR (0.50) | CCKARCCKBRCBLB | |
| SCHEMBL24612257 | 0.89 | NOTCH1 (0.39) | NOTCH1RBPJCCKBRCBLBNOTCH3 | |
| SCHEMBL24612258 | 0.89 | NOTCH1 (0.39) | NOTCH1RBPJCCKBRCBLBNOTCH3 | |
| SCHEMBL20369883 | 0.85 | CBLB (0.38) | CCKARCCKBRCBLBKDM4EALDH1A1 | |
| SCHEMBL20370071 | 0.85 | CBLB (0.38) | CCKARCCKBRCBLBKDM4EALDH1A1 | |
| SCHEMBL20867288 | 0.85 | CBLB (0.46) | NOTCH1RBPJCCKARCCKBRCBLB | |
| SCHEMBL20866780 | 0.85 | CBLB (0.46) | NOTCH1RBPJCCKARCCKBRCBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019067864-A1 | COMBINATION PHARMACEUTICAL AGENTS AS RSV INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2019-04-04 | — | — | WO | disclosed |