SCHEMBL20370440

SCHEMBL20370440

C=CC(=O)N(C)CCOc1ccc(-c2ccc(-c3ccc(CCCCC)cc3)cc2F)cc1F

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ RARB P10826 4/20 0.45
▸ RARA P10276 1/20 0.45
▸ RARG P13631 1/20 0.45
▸ S1PR1 P21453 1/20 0.42
▸ THRB P10828 6/20 0.41
▸ THRA P10827 5/20 0.41
▸ BTK Q06187 5/20 0.39
▸ PTPN1 P18031 1/20 0.38
▸ PTPN6 P29350 1/20 0.38
▸ PTPN11 Q06124 1/20 0.38
▸ SLC6A9 P48067 1/20 0.38
▸ MEN1 O00255 1/20 0.37
▸ KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19855476 0.91 RARB (0.48) RARBRARARARGS1PR1THRB
SCHEMBL19854082 0.90 RARB (0.48) RARBRARARARGS1PR1THRB
SCHEMBL20370439 0.90 RARB (0.48) RARBRARARARGS1PR1THRB
SCHEMBL19854078 0.86 RARB (0.55) RARBRARARARGTHRBTHRA
SCHEMBL19855477 0.86 RARB (0.49) RARBRARARARGTHRBTHRA
SCHEMBL19855040 0.84 RARB (0.48) RARBRARARARGS1PR1THRB
SCHEMBL19854448 0.84 RARB (0.47) RARBRARARARGS1PR1THRB
SCHEMBL19854043 0.83 BTK (0.40) THRBTHRABTK
SCHEMBL20370443 0.83 RARB (0.48) RARBRARARARGTHRBTHRA
SCHEMBL19854449 0.83 THRB (0.43) RARBRARARARGS1PR1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 — — US disclosed
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2020-05-26 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2018-07-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195005-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE SP1, MBD2, PAXBP1 RARB 1437/4885RARA 1599/4885RARG 598/4885
US-10662379-B2 Polymerizable polar compound, liquid crystal composition and liquid crystal display device SP1, MBD2, PAXBP1 RARB 1437/4885RARA 1599/4885RARG 598/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback