Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 14/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 6/20 | 0.38 |
| ▸ | CCNC | P24863 | 5/20 | 0.38 |
| ▸ | TYK2 | P29597 | 4/20 | 0.38 |
| ▸ | JAK3 | P52333 | 4/20 | 0.38 |
| ▸ | JAK1 | P23458 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 3/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.37 |
| ▸ | CDC7 | O00311 | 2/20 | 0.37 |
| ▸ | PLK4 | O00444 | 2/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.37 |
| ▸ | CDK1 | P06493 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2009613 | 0.82 | MET (0.55) | JAK2PDPK1KDM4EMAPK1RPS6KA3 | |
| SCHEMBL2013526 | 0.72 | MET (0.44) | JAK2PDPK1KDM4ECDK8CCNC | |
| SCHEMBL2011596 | 0.71 | MET (0.44) | JAK2PDPK1KDM4EGAATYK2 | |
| SCHEMBL4994801 | 0.71 | MET (0.55) | KDM4ERPS6KA5MAPK1RPS6KA3 | |
| SCHEMBL13685509 | 0.71 | MET (0.44) | JAK2PDPK1KDM4ECDK8CCNC | |
| SCHEMBL1414765 | 0.70 | MET (0.66) | JAK2PDPK1KDM4EMAPK1RPS6KA3 | |
| SCHEMBL29521013 | 0.70 | JAK2 (0.60) | JAK2PDPK1KDM4ECYP3A4GAA | |
| SCHEMBL3657599 | 0.70 | JAK2 (0.60) | JAK2PDPK1KDM4ECYP3A4GAA | |
| SCHEMBL2010339 | 0.70 | MET (0.53) | KDM4ERPS6KA5MAPK1RPS6KA3 | |
| SCHEMBL14486911 | 0.69 | JAK2 (0.50) | JAK2PDPK1KDM4ECYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011067189-A2 | CMET INHIBITORS FOR TREATING ENDOMETRIOSIS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-06-09 | — | — | WO | claimed |