Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.57 |
| ▸ | CHRM3 | P20309 | 16/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD1 | P21728 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16697625 | 0.89 | ADRB2 (0.56) | ADRB2CHRM3DRD2DRD1DRD4 | |
| SCHEMBL20373868 | 0.89 | ADRB2 (0.56) | ADRB2CHRM3DRD2DRD1DRD4 | |
| SCHEMBL16697629 | 0.89 | ADRB2 (0.56) | ADRB2CHRM3DRD2DRD1DRD4 | |
| SCHEMBL20357834 | 0.89 | ADRB2 (0.56) | ADRB2CHRM3DRD2DRD1DRD4 | |
| SCHEMBL20357835 | 0.89 | ADRB2 (0.56) | ADRB2CHRM3DRD2DRD1DRD4 | |
| SCHEMBL20357836 | 0.89 | ADRB2 (0.56) | ADRB2CHRM3DRD2DRD1DRD4 | |
| SCHEMBL20373848 | 0.88 | ADRB2 (0.60) | ADRB2CHRM3DRD2DRD1DRD4 | |
| SCHEMBL15771686 | 0.88 | CHRM3 (0.77) | ADRB2CHRM3 | |
| SCHEMBL15771687 | 0.88 | CHRM3 (0.77) | ADRB2CHRM3 | |
| SCHEMBL15771684 | 0.88 | CHRM3 (0.77) | ADRB2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345904-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | Chiesi Farmaceutici S.p.a. (IT) | 2018-07-11 | — | — | EP | disclosed |