Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 7/20 | 0.42 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 7/20 | 0.38 |
| ▸ | BRD2 | P25440 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16896952 | 0.85 | BRD4 (0.51) | SCN9AFGFR4BRD4BRD2CYP3A4 | |
| SCHEMBL18326377 | 0.82 | SCN9A (0.47) | SCN9AFGFR4BRD4CYP2C9ALDH1A1 | |
| SCHEMBL16896810 | 0.77 | BRD4 (0.39) | FGFR4BRD4BRD2CYP3A4CYP2C9 | |
| SCHEMBL16896811 | 0.74 | BRD4 (0.39) | SCN9ABRD4BRD2CYP3A4CYP2C9 | |
| SCHEMBL20373577 | 0.73 | SCN9A (0.41) | SCN9AFGFR4CYP2C9ALDH1A1KMT2A | |
| SCHEMBL18317183 | 0.73 | BRD4 (0.43) | BRD4BRD2CYP3A4CYP2C9BRD3 | |
| SCHEMBL16896800 | 0.70 | BRD4 (0.53) | SCN9AFGFR4BRD4BRD2CYP3A4 | |
| SCHEMBL16896915 | 0.69 | BRD4 (0.51) | SCN9ABRD4BRD2CYP3A4CYP2C9 | |
| SCHEMBL20357613 | 0.69 | BRD4 (0.43) | SCN9AFGFR4BRD4BRD2CYP3A4 | |
| SCHEMBL16896733 | 0.69 | BRD4 (0.53) | SCN9ABRD4BRD2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092227-B1 | BICYCLIC HETEROCYCLIC DERIVATIVES AS BROMODOMAIN INHIBITORS | ORION CORP (FI) | 2018-07-11 | — | — | EP | disclosed |