Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 6/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18326377 | 0.80 | SCN9A (0.47) | SCN9AFGFR4KMT2ABCHEACHE | |
| SCHEMBL20373765 | 0.77 | BRD4 (0.45) | SCN9AFGFR4POLBKMT2ABCHE | |
| SCHEMBL20373753 | 0.76 | SCN9A (0.40) | SCN9APOLBKMT2APDE10ASMN1; SMN2 | |
| SCHEMBL16896952 | 0.73 | BRD4 (0.51) | SCN9AFGFR4CYP2C9 | |
| SCHEMBL20373578 | 0.73 | SCN9A (0.42) | SCN9AFGFR4KMT2ABCHEACHE | |
| SCHEMBL20373288 | 0.66 | S1PR3 (0.37) | PDE10ASMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL18326372 | 0.65 | SCN9A (0.47) | SCN9AFGFR4KMT2ABCHEACHE | |
| SCHEMBL20373356 | 0.65 | PLA2G2A (0.39) | POLBKMT2APDE10ASMN1; SMN2ALDH1A1 | |
| SCHEMBL18326375 | 0.65 | SCN9A (0.46) | SCN9AFGFR4KMT2ABCHEACHE | |
| SCHEMBL20357613 | 0.64 | BRD4 (0.43) | SCN9AFGFR4CYP1A2CYP2C9ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092227-B1 | BICYCLIC HETEROCYCLIC DERIVATIVES AS BROMODOMAIN INHIBITORS | ORION CORP (FI) | 2018-07-11 | — | — | EP | disclosed |