Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 19/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.62 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.61 |
| ▸ | CHRM3 | P20309 | 15/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28441272 | 0.92 | ADRB2 (0.74) | ADRB2ADRB1ADRB3CHRM3 | |
| SCHEMBL28441274 | 0.92 | ADRB2 (0.74) | ADRB2ADRB1ADRB3CHRM3 | |
| SCHEMBL15777637 | 0.89 | ADRB2 (0.66) | ADRB2CHRM3 | |
| SCHEMBL17978746 | 0.89 | ADRB2 (0.84) | ADRB2CHRM3 | |
| SCHEMBL17979000 | 0.89 | ADRB2 (0.84) | ADRB2CHRM3 | |
| SCHEMBL15778220 | 0.89 | ADRB2 (0.66) | ADRB2CHRM3 | |
| SCHEMBL20357784 | 0.89 | ADRB2 (0.66) | ADRB2CHRM3 | |
| SCHEMBL15778222 | 0.89 | ADRB2 (0.66) | ADRB2CHRM3 | |
| SCHEMBL17978859 | 0.85 | ADRB2 (0.87) | ADRB2CHRM3 | |
| SCHEMBL17978862 | 0.85 | ADRB2 (0.87) | ADRB2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3345904-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | Chiesi Farmaceutici S.p.a. (IT) | 2018-07-11 | — | — | EP | disclosed |